en
Scientific article
English

Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation

Published inAlzheimer's & dementia, vol. 11, no. 2, p. 184-194
Publication date2015
Abstract

Hippocampal volumetry on magnetic resonance imaging is recognized as an Alzheimer's disease (AD) biomarker, and manual segmentation is the gold standard for measurement. However, a standard procedure is lacking. We operationalize and quantitate landmark differences to help a Delphi panel converge on a set of landmarks.

Keywords
  • Aged
  • Alzheimer Disease/pathology
  • Atrophy
  • Delphi Technique
  • Female
  • Hippocampus/anatomy & histology/pathology
  • Humans
  • Image Processing, Computer-Assisted/methods
  • Imaging, Three-Dimensional/methods
  • Magnetic Resonance Imaging/instrumentation/methods
  • Male
  • Mild Cognitive Impairment/pathology
  • Neuroimaging/methods
  • Organ Size
  • Reproducibility of Results
Citation (ISO format)
BOCCARDI, Marina et al. Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation. In: Alzheimer’s & dementia, 2015, vol. 11, n° 2, p. 184–194. doi: 10.1016/j.jalz.2013.03.001
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Article (Published version)
accessLevelRestricted
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ISSN of the journal1552-5260
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