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Title

DHEA replacement for postmenopausal women: have we been looking in the right direction?

Authors
Genazzani, A R
Published in Climacteric. 2015, vol. 18, no. 5, p. 669-671
Abstract Dehydroepiandrosterone (DHEA) and its sulfate represent the most abundant sex steroid in humans. In addition to age-related reduction, serum DHEA shows large interindividual variability. Although cross-sectional studies suggest that lower levels are associated with cardiovascular, cognitive and sexual impairment in women, clinical trials of oral DHEA replacement have failed to show benefits. However, current evidence is too imprecise to draw definite conclusions.
Keywords Adjuvants, Immunologic/therapeutic useDehydroepiandrosterone/therapeutic useEstrogen Replacement Therapy/adverse effects/methodsFemaleHumansMiddle AgedPostmenopause/drug effects
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PMID: 25961114
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GENAZZANI, A R, PLUCHINO, Nicola. DHEA replacement for postmenopausal women: have we been looking in the right direction?. In: Climacteric, 2015, vol. 18, n° 5, p. 669-671. https://archive-ouverte.unige.ch/unige:89555

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Deposited on : 2016-11-30

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