• Home
  1. Home
  2. Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat
Scientific article
English

Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat

ContributorsSchraermeyer, U; Kayatz, P; Thumann, Gabrieleorcid; Luther, T T; Szurman, P; Kociok, N; Bartz-Schmidt, K U
Published inGraefe's archive for clinical and experimental ophthalmology, vol. 238, no. 12, p. 979-984
Publication date2000
Abstract

Trophic factors [e.g. basic fibroblast growth factor (bFGF)] released by transplanted retinal pigment epithelial (RPE) cells are able to slow down the hereditary degeneration of the retina in the Royal College of Surgeons rat in sites distant from the site of transplantation where rod outer segment (ROS) phagocytic activity is not reconstituted by the transplants.

Keywords
  • Animals
  • Cell Survival/physiology
  • Cell Transplantation
  • Choroid/surgery
  • Image Processing, Computer-Assisted
  • Iris/cytology
  • Photoreceptor Cells, Vertebrate/pathology/physiology
  • Pigment Epithelium of Eye/transplantation/ultrastructure
  • Rats
  • Rats, Mutant Strains
  • Retinal Degeneration/genetics/pathology/prevention & control
Affiliation entities Not a UNIGE publication
Citation (ISO format)
SCHRAERMEYER, U et al. Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat. In: Graefe’s archive for clinical and experimental ophthalmology, 2000, vol. 238, n° 12, p. 979–984. doi: 10.1007/s004170000194
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0721-832X
481views
1downloads

Technical informations

Creation22/09/2016 09:51:00
First validation22/09/2016 09:51:00
Update20/02/2026 12:48:52
Status update20/02/2026 12:48:52
Last indexation20/02/2026 12:52:24
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack