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Title

Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat

Authors
Schraermeyer, U
Kayatz, P
Luther, T T
Szurman, P
Kociok, N
Bartz-Schmidt, K U
Published in Graefe's Archive for Clinical and Experimental Ophthalmology. 2000, vol. 238, no. 12, p. 979-984
Abstract Trophic factors [e.g. basic fibroblast growth factor (bFGF)] released by transplanted retinal pigment epithelial (RPE) cells are able to slow down the hereditary degeneration of the retina in the Royal College of Surgeons rat in sites distant from the site of transplantation where rod outer segment (ROS) phagocytic activity is not reconstituted by the transplants.
Keywords AnimalsCell Survival/physiologyCell TransplantationChoroid/surgeryImage Processing, Computer-AssistedIris/cytologyPhotoreceptor Cells, Vertebrate/pathology/physiologyPigment Epithelium of Eye/transplantation/ultrastructureRatsRats, Mutant StrainsRetinal Degeneration/genetics/pathology/prevention & control
Identifiers
PMID: 11196361
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SCHRAERMEYER, U et al. Transplantation of iris pigment epithelium into the choroid slows down the degeneration of photoreceptors in the RCS rat. In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2000, vol. 238, n° 12, p. 979-984. https://archive-ouverte.unige.ch/unige:89342

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Deposited on : 2016-11-23

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