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Ultrastructural changes after artificial retinal detachment with modified retinal adhesion

Szurman, Peter
Roters, Sigrid
Grisanti, Salvatore
Aisenbrey, Sabine
Schraermeyer, Ulrich
Lüke, Matthias
Bartz-Schmidt, Karl Ulrich
Published in Investigative Ophthalmology & Visual Science. 2006, vol. 47, no. 11, p. 4983-4989
Abstract Artificial retinal detachment is increasingly used in submacular surgery. However, overcoming physiological retinal adhesiveness by subretinal fluid injection is suspected to cause cellular damage and thus to limit visual rehabilitation. This experimental study was designed to examine the ultrastructural changes induced by retinal detachment under vitrectomy conditions and to evaluate factors that reduce adhesiveness and minimize cellular damage.
Keywords AdhesivenessAnimalsCalcium/pharmacologyHot TemperatureIschemia/metabolismIsotonic SolutionsMicroscopy, Electron, ScanningOsmolar ConcentrationPhotoreceptor Cells/metabolism/ultrastructurePigment Epithelium of Eye/metabolism/ultrastructureRabbitsRetina/metabolism/ultrastructureRetinal Detachment/pathologyVitrectomy
PMID: 17065517
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SZURMAN, Peter et al. Ultrastructural changes after artificial retinal detachment with modified retinal adhesion. In: Investigative Ophthalmology & Visual Science, 2006, vol. 47, n° 11, p. 4983-4989. doi: 10.1167/iovs.06-0491

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Deposited on : 2016-11-23

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