Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

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Title		Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease
Authors		Gariani, Karim Ryu, Dongryeol Menzies, Keir J Yi, Hyon-Seung Stein, Sokrates Zhang, Hongbo Perino, Alessia Lemos, Vera Katsyuba, Elena Jha, Pooja Vijgen, Sandrine Elisabeth V Rubbia-Brandt, Laura Kim, Yong Kyung Kim, Jung Tae Kim, Koon Soon Shong, Minho Schoonjans, Kristina Auwerx, Johan show all authors [1 - 18]
Published in		Journal of Hepatology. 2017, vol. 66, no. 1, p. 132-141
Abstract		To date, no pharmacological therapy has been approved for non-alcoholic fatty liver disease (NAFLD). The aim of the present study was to evaluate the therapeutic potential of poly ADP-ribose polymerase (PARP) inhibitors in mouse models of NAFLD.
Identifiers		DOI: 10.1016/j.jhep.2016.08.024 PMID: 27663419
Full text		Article (Published version) (2.8 MB) - Free access
Structures		Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Research group		Métastases du foie (657)
Citation (ISO format)		GARIANI, Karim et al. Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. In: Journal of Hepatology, 2017, vol. 66, n° 1, p. 132-141. doi: 10.1016/j.jhep.2016.08.024 https://archive-ouverte.unige.ch/unige:89086