UNIGE document Scientific Article
previous document  unige:88725  next document
add to browser collection
Title

Chemoselective Dimerization of Phosphates

Authors
Hofer, Alexandre
Marques, Elia
Kieliger, Nicole
Gatter, Sarah-Kirsten N
Jordi, Sara
Ferrari, Elena
show hidden authors show all authors [1 - 10]
Published in Organic Letters. 2016, vol. 18, no. 13, p. 3222-3225
Abstract A methodology for the synthesis of oligophosphate conjugates using phosphordiamidites is described. This strategy facilitates the straightforward preparation of C2-symmetric dinucleoside tri-, penta-, and heptaphosphates. Moreover, unsymmetric compounds such as thiamine adenosine triphosphate and thiamine cytidine triphosphate can be prepared. The material is used to study the inhibitory activity of thiaminylated nucleotides against adenosine diphosphate ribosyltransferases.
Identifiers
PMID: 27308921
Full text
Article (Published version) (712 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
HOFER, Alexandre et al. Chemoselective Dimerization of Phosphates. In: Organic Letters, 2016, vol. 18, n° 13, p. 3222-3225. https://archive-ouverte.unige.ch/unige:88725

44 hits

1 download

Update

Deposited on : 2016-11-07

Export document
Format :
Citation style :