UNIGE document Scientific Article
previous document  unige:88535  next document
add to browser collection

Clinical decision rules and D-Dimer in venous thromboembolism: current controversies and future research priorities

Rodger, Marc A
Le Gal, Gregoire
Wells, Philip
Baglin, Trevor
Aujesky, Drahomir
Palareti, Gualtiero
Huisman, Menno
show hidden authors show all authors [1 - 9]
Published in Thrombosis research. 2014, vol. 134, no. 4, p. 763-768
Abstract Venous thromboembolism (VTE) is a potentially lethal clinical condition that is suspected in patients with common clinical complaints, in many and varied, clinical care settings. Once VTE is diagnosed, optimal therapeutic management (thrombolysis, IVC filters, type and duration of anticoagulants) and ideal therapeutic management settings (outpatient, critical care) are also controversial. Clinical prediction tools, including clinical decision rules and D-Dimer, have been developed, and some validated, to assist clinical decision making along the diagnostic and therapeutic management paths for VTE. Despite these developments, practice variation is high and there remain many controversies in the use of the clinical prediction tools. In this narrative review, we highlight challenges and controversies in VTE diagnostic and therapeutic management with a focus on clinical decision rules and D-Dimer.
Keywords Anticoagulants/therapeutic useDecision Support Systems, ClinicalFibrin Fibrinogen Degradation Products/analysisHumansPulmonary Embolism/diagnosis/therapyResearchVenous Thromboembolism/diagnosis/therapy
PMID: 25129416
Full text
Article (Published version) (255 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research group La maladie thromboembolique veineuse (808)
(ISO format)
RODGER, Marc A et al. Clinical decision rules and D-Dimer in venous thromboembolism: current controversies and future research priorities. In: Thrombosis research, 2014, vol. 134, n° 4, p. 763-768. doi: 10.1016/j.thromres.2014.07.031 https://archive-ouverte.unige.ch/unige:88535

366 hits

0 download


Deposited on : 2016-11-01

Export document
Format :
Citation style :