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Scientific article
English

Blocking interferon γ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis

Published inAnnals of the rheumatic diseases, vol. 75, no. 6, p. 1177-1186
Publication date2016
Abstract

Interferon γ (IFNγ) is considered a seminal cytokine in the pathogenesis of giant cell arteritis (GCA), but its functional role has not been investigated. We explored changes in infiltrating cells and biomarkers elicited by blocking IFNγ with a neutralising monoclonal antibody, A6, in temporal arteries from patients with GCA.

Citation (ISO format)
CORBERA-BELLALTA, Marc et al. Blocking interferon γ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis. In: Annals of the rheumatic diseases, 2016, vol. 75, n° 6, p. 1177–1186. doi: 10.1136/annrheumdis-2015-208371
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ISSN of the journal0003-4967
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Creation08/31/2016 11:00:00 AM
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Update time03/15/2023 12:51:58 AM
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