Scientific article

No association between DUP25 and anxiety disorders

Publication date2004

Gratacos et al. [2001: Cell 106:367-379] described an interstitial duplication dup(15)q24q26 (DUP25) in patients with anxiety disorders; this duplication was found in approximately 90% of patients and in 7% of controls. In order to determine if DUP25 is present in additional individuals susceptible to panic attacks, we tested 44 patients with anxiety disorders, using probes 251c23 and 216c14 mapping in the 15q24 and 15q26 region. We have not detected any DUP25. Our results suggest that DUP25 is not common in people with anxiety disorders in the population tested here.

  • Adolescent
  • Adult
  • Aged
  • Anxiety Disorders/epidemiology/ genetics
  • Case-Control Studies
  • Chromosomes, Human, Pair 15
  • DNA Probes
  • Female
  • Gene Duplication
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Humans
  • In Situ Hybridization, Fluorescence
  • Male
  • Middle Aged
  • Molecular Epidemiology
Citation (ISO format)
HENRICHSEN, C. N. et al. No association between DUP25 and anxiety disorders. In: American journal of medical genetics. Part B, Neuropsychiatric genetics, 2004, vol. 128B, n° 1, p. 80–83. doi: 10.1002/ajmg.b.30037
Updates (1)
ISSN of the journal1552-4841

Technical informations

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