Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome
Published inHuman molecular genetics, vol. 9, no. 12, p. 1853-1864
Publication date2000
Abstract
Keywords
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Behavior, Animal
- Chromosomes, Bacterial
- DNA-Binding Proteins/genetics/ physiology
- Disease Models, Animal
- Down Syndrome/ etiology
- Drosophila Proteins
- Female
- Gene Dosage
- Gene Expression Profiling
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Motor Activity
- Nuclear Proteins/genetics/ physiology
- Pain Measurement
- Phenotype
- Social Behavior
- Stress, Physiological
- Trisomy
Affiliation
Citation (ISO format)
CHRAST, R. et al. Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome. In: Human molecular genetics, 2000, vol. 9, n° 12, p. 1853–1864. doi: 10.1093/hmg/9.12.1853
Main files (1)
Article
Identifiers
- PID : unige:8687
- DOI : 10.1093/hmg/9.12.1853
- PMID : 10915774
Commercial URLhttp://hmg.oxfordjournals.org/cgi/reprint/9/12/1853.pdf
ISSN of the journal0964-6906