UNIGE document Scientific Article
previous document  unige:86190  next document
add to browser collection
Title

Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1

Authors
Deutsch, Eric W
Overall, Christopher M
Van Eyk, Jennifer E
Baker, Mark S
Paik, Young-Ki
Weintraub, Susan T
Martens, Lennart
show hidden authors show all authors [1 - 15]
Published in Journal of Proteome Research. 2016, vol. 15, no. 11, p. 3961-3970
Abstract Every data-rich community research effort requires a clear plan for ensuring the quality of the data interpretation and comparability of analyses. To address this need within the Human Proteome Project (HPP) of the Human Proteome Organization (HUPO), we have developed through broad consultation a set of mass spectrometry data interpretation guidelines that should be applied to all HPP data contributions. For submission of manuscripts reporting HPP protein identification results, the guidelines are presented as a one-page checklist containing fifteen essential points followed by two pages of expanded description of each. Here, we present an overview of the guidelines and provide an in-depth description of each of the fifteen elements to facilitate understanding of the intentions and rationale behind the guidelines, both for authors and for reviewers. Broadly, these guidelines provide specific directions regarding how HPP data are to be submitted to mass spectrometry data repositories, how error analysis should be presented, and how detection of novel proteins should be supported with additional confirmatory evidence. These guidelines, developed by the HPP community, are presented to the broader scientific community for further discussion.
Identifiers
PMID: 27490519
Full text
Article (Preprint) (739 Kb) - public document Free access
Structures
Research groups SIB Swiss Institute of Bioinformatics
Calipho (80)
Citation
(ISO format)
DEUTSCH, Eric W et al. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. In: Journal of Proteome Research, 2016, vol. 15, n° 11, p. 3961-3970. https://archive-ouverte.unige.ch/unige:86190

170 hits

48 downloads

Update

Deposited on : 2016-08-18

Export document
Format :
Citation style :