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Scientific article
English

Dynamic-Electromembrane Extraction: A Technical Development for the Extraction of Neuropeptides

Contributors

Drouin, Nicolas; Rudaz, Serge; Schappler, Julie

Published in

Analytical chemistry, vol. 88, p. 5308-5315

Publication date

2016

Abstract

In this work, a dynamic-electromembrane extraction (d-EME) device was developed for the extraction of neuropeptides. On the basis of a thin polypropylene hollow fiber (50 μm of wall-thickness and 280 μm i.d.), this setup allowed for a continual renewal of the acceptor compartment. Because of the reduced size of the device, high preconcentration factors were obtained (up to 50-fold). The extraction remained constant regardless of the extraction time (from 15 to 45 min); accordingly, this new setup minimized the effect of electrolysis on extraction performance while enabling high extraction yield (up to 72%) for most lipophilic neuropeptides.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

DROUIN, Nicolas, RUDAZ, Serge, SCHAPPLER, Julie. Dynamic-Electromembrane Extraction: A Technical Development for the Extraction of Neuropeptides. In: Analytical chemistry, 2016, vol. 88, p. 5308–5315. doi: 10.1021/acs.analchem.6b00559

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0003-2700
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Technical informations

Creation

10/08/2016 11:26:00

First validation

10/08/2016 11:26:00

Update

15/03/2023 00:37:00

Status update

15/03/2023 00:36:59

Last indexation

18/03/2025 09:22:27
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