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Isolation and initial characterization of the mouse Dnmt3l gene

Aapola, Ulla
Krohn, K.
Peterson, P.
Published in Cytogenetics and cell genetics. 2001, vol. 92, no. 1-2, p. 122-126
Abstract We have isolated and sequenced the mouse zinc finger gene, Dnmt3l (DNA cytosine-5-methyltransferase 3-like), on mouse chromosome 10, showing similarity to members of the DNMT3/Dnmt3 family. The Dnmt3l protein contains an ADD zinc finger, which Dnmt3l shares with other Dnmt3 family members and Atrx. RT-PCR analysis showed Dnmt3l expression in testis, thymus, ovary, and heart, as well as in 7-day, 15-day, and 17-day mouse embryos.
Keywords Amino Acid SequenceAnimalsCOS CellsDNA (Cytosine-5-)-Methyltransferase/analysis/chemistry/ geneticsEmbryo, Mammalian/enzymologyExons/geneticsExpressed Sequence TagsFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalMaleMiceMice, Inbred BALB CMolecular Sequence DataOvary/enzymologyPhysical Chromosome MappingPolymorphism, Single Nucleotide/geneticsProtein Structure, TertiaryRNA, Messenger/analysis/geneticsReverse Transcriptase Polymerase Chain ReactionSequence AlignmentSequence Analysis, DNATestis/enzymologyThymus Gland/enzymologyZinc Fingers
PMID: 11306809
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AAPOLA, Ulla et al. Isolation and initial characterization of the mouse Dnmt3l gene. In: Cytogenetics and cell genetics, 2001, vol. 92, n° 1-2, p. 122-126. https://archive-ouverte.unige.ch/unige:8594

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Deposited on : 2010-07-12

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