Transplantation of PEDF-transfected pigment epithelial cells inhibits corneal neovascularization in a rabbit model

Kuerten, David; Johnen, Sandra; Harmening, Nina; Souteyrand, Georges; Walter, Peter; Thumann, Gabriele

doi:10.1007/s00417-015-2954-x

Scientific article

English

Transplantation of PEDF-transfected pigment epithelial cells inhibits corneal neovascularization in a rabbit model

ContributorsKuerten, David; Johnen, Sandra; Harmening, Nina; Souteyrand, Georges; Walter, Peter; Thumann, Gabriele

Published inGraefe's archive for clinical and experimental ophthalmology, vol. 253, no. 7, p. 1061-1069

Publication date2015

Abstract

The purpose of this study was to investigate the effect of recombinant pigment epithelium-derived factor (rPEDF), secreted by ARPE-19 cells transfected with the human PEDF gene and transplanted subconjunctivally in normal and in rabbits in which corneal neovascularization was elicited by a chemical burn.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Research groups

Ophtalmologie expérimentale (925)

Citation (ISO format)

KUERTEN, David et al. Transplantation of PEDF-transfected pigment epithelial cells inhibits corneal neovascularization in a rabbit model. In: Graefe’s archive for clinical and experimental ophthalmology, 2015, vol. 253, n° 7, p. 1061–1069. doi: 10.1007/s00417-015-2954-x

Article (Published version)

OA NATIONAL

Identifiers

PID : unige:85689
DOI : 10.1007/s00417-015-2954-x
PMID : 25690979

Additional URL for this publicationhttp://link.springer.com/10.1007/s00417-015-2954-x

Journal ISSN0721-832X

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Creation05/08/2016 11:28:00

First validation05/08/2016 11:28:00

Update time15/03/2023 00:36:11

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Transplantation of PEDF-transfected pigment epithelial cells inhibits corneal neovascularization in a rabbit model

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