Nowadays, adipose tissue is considered as a mutli-function organ and more recently a source of regenerative cells. Therefore, adipose tissue has gained significant attention. How to reduce it when it is in excess? How to take advantage of it? And even how to increase it when needed? In this thesis, we will demonstrate a) how adipose reduction by plastic surgery can improve quality of life and weight loss, b) how to improve fat grafting outcome by adding platelet-rich plasma (PRP), c) how to have a safer and more effective technique for in vitro adipose-derived stem cells expansion by using autologous PRP instead of actual cell culture media, and e) finally, how to increase soft tissue by an innovative technique composed of microspheres loaded with lipids, which could increase the adipose tissue volume in situ.