In 1721, when Geneva is threatened by a terrible epidemic devastating the south of France, the physician Jean-Jaques Manget states that “The Magistrates must establish a good Policy in time of plague”; and asks himself how it is possible to carry on “without good Regulations?”.The State Archives of Geneva hold a draft consisting of 72 articles concerning health policy meant to be applied in case of plague.This is a remarkable document that enables an overview of the city's organisation in times of plague; it also allows to analyse some of the medical and sanitary theories this organisation is based on.