UNIGE document Scientific Article
previous document  unige:84819  next document
add to browser collection
Title

Analysis of amphetamines by capillary electrophoresis and liquid chromatography: application to drug seizures and cross-validation

Authors
Giroud, C.
Rivier, L.
Published in Forensic Science International. 1997, vol. 86, no. 1-2, p. 1-13
Abstract Two methods, capillary electrophoresis (CE) and liquid chromatography (LC), have been developed for the separation and quantitation of amphetamines found in illicit drug seizures. These methods allowed us to determine, within less than 8 min and without interference from adulterants, the presence of six current amphetamines. No significant statistical differences between both validated methods were observed as linearity, precision, accuracy and limits of detection and quantitation were similar. However, the order of elution of amphetamines and of adulterants was different; hence, these methods proved to be orthogonal which is very convenient for forensic analysis. Further, CE and LC were applied to the analysis of 13 seized tablets with quantitative results statistically similar. Qualitative results were also confirmed by GC-MS procedure.
Keywords AmphetaminesHPLCCapillary electrophoresisIllicit drugsValidation
Identifiers
Full text
Structures
Citation
(ISO format)
SADEGHIPOUR, Farshid et al. Analysis of amphetamines by capillary electrophoresis and liquid chromatography: application to drug seizures and cross-validation. In: Forensic Science International, 1997, vol. 86, n° 1-2, p. 1-13. https://archive-ouverte.unige.ch/unige:84819

111 hits

1 download

Update

Deposited on : 2016-06-28

Export document
Format :
Citation style :