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Title

Prognostic stratification of acute pulmonary embolism: focus on clinical aspects, imaging, and biomarkers

Authors
Masotti, Luca
Antonelli, Fabio
Landini, Giancarlo
Cappelli, Roberto
Ray, Patrick
Published in Vascular Health and Risk Management. 2009, vol. 5, no. 4, p. 567-75
Abstract Pulmonary embolism (PE) represents a common disease in emergency medicine and guidelines for diagnosis and treatment have had wide diffusion. However, PE morbidity and mortality remain high, especially when associated to hemodynamic instability or right ventricular dysfunction. Prognostic stratification to identify high risk patients needing to receive more aggressive pharmacological and closer monitoring is of utmost importance. Modern guidelines for management of acute PE are based on risk stratification using either clinical, radiological, or laboratory findings. This article reviews the modern treatment of acute PE, which is customized upon patient prognosis. Accordingly the current risk stratification tools described in the literature such as clinical scores, echocardiography, helical computer tomography, and biomarkers will be reviewed.
Keywords Acute DiseaseBiomarkers/bloodDiagnostic Imaging/methodsEchocardiographyElectrocardiographyHumansPatient SelectionPractice Guidelines as TopicPredictive Value of TestsPrognosisPulmonary Embolism/blood/diagnosis/drug therapy/etiology/mortalityRisk AssessmentRisk FactorsSeverity of Illness IndexThrombolytic TherapyTomography, Spiral Computed
Identifiers
PMID: 19649307
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Article (Published version) (474 Kb) - public document Free access
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Research group Chimie et protéomique clinique (270)
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MASOTTI, Luca et al. Prognostic stratification of acute pulmonary embolism: focus on clinical aspects, imaging, and biomarkers. In: Vascular Health and Risk Management, 2009, vol. 5, n° 4, p. 567-75. https://archive-ouverte.unige.ch/unige:84730

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Deposited on : 2016-06-24

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