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Title

Evidence for sex transformation of germline cells in ovarian tumor mutants of Drosophila

Authors
Wei, Grace
Oliver, Brian
Mahowald, Anthony P.
Published in Developmental Biology. 1994, vol. 161, no. 1, p. 318-320
Abstract Mutations at a few genetic loci in Drosophila cause ovarian tumors with hundreds of poorly differentiated germ cells. We examined several of these mutants to test the hypothesis that such ovarian tumors contain sex-transformed cells. By testing for expression of male germline traits, we determined that partial germline sex transformation occurs in otu, snf, Sxlfs, and bam ovarian tumors. Thus these genes are likely to be required for proper establishment of germline sexual identity.
Keywords AnimalsDrosophila/geneticsFemaleGerm Cells/physiologyMaleMutationOvarian Neoplasms/geneticsSex Determination AnalysisTubulin/genetics
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PMID: 8293883
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WEI, Grace et al. Evidence for sex transformation of germline cells in ovarian tumor mutants of Drosophila. In: Developmental Biology, 1994, vol. 161, n° 1, p. 318-320. https://archive-ouverte.unige.ch/unige:84376

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Deposited on : 2016-06-09

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