

Other version: http://linkinghub.elsevier.com/retrieve/pii/S0960894X13007580
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Convenient synthesis of heterobifunctional poly(ethylene glycol) suitable for the functionalization of iron oxide nanoparticles for biomedical applications |
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Published in | Bioorganic & Medicinal Chemistry Letters. 2013, vol. 23, no. 17, p. 5006-5010 | |
Abstract | A straightforward route is proposed for the multi-gram scale synthesis of heterobifunctional poly(ethylene glycol) (PEG) oligomers containing combination of triethyloxysilane extremity for surface modification of metal oxides and amino or azido active end groups for further functionalization. The suitability of these PEG derivatives to be conjugated to nanomaterials was shown by pegylation of ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs), followed by functionalization with small peptide ligands for biomedical applications. | |
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![]() ![]() Other version: http://linkinghub.elsevier.com/retrieve/pii/S0960894X13007580 |
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Research group | Groupe Wolf | |
Citation (ISO format) | PASSEMARD, Solène et al. Convenient synthesis of heterobifunctional poly(ethylene glycol) suitable for the functionalization of iron oxide nanoparticles for biomedical applications. In: Bioorganic & Medicinal Chemistry Letters, 2013, vol. 23, n° 17, p. 5006-5010. doi: 10.1016/j.bmcl.2013.06.037 https://archive-ouverte.unige.ch/unige:84340 |