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Scientific article
English

Plasmonic Tipless Pyramid Arrays for Cell Poration

Contributors

Courvoisier, Sébastien; Saklayen, Nabiha; Huber, Marinus; Chen, Jun; Diebold, Eric D.; Bonacina, Luigi; Wolf, Jean-Pierre; Mazur, Eric

Published in

Nano letters, vol. 15, no. 7, p. 4461-4466

Publication date

2015

Abstract

Improving the efficiency, cell survival, and throughput of methods to modify and control the genetic expression of cells is of great benefit to biology and medicine. We investigate, both computationally and experimentally, a nanostructured substrate made of tipless pyramids for plasmonic-induced transfection. By optimizing the geometrical parameters for an excitation wavelength of 800 nm, we demonstrate a 100-fold intensity enhancement of the electric near field at the cell–substrate contact area, while the low absorption typical for gold is maintained. We demonstrate that such a substrate can induce transient poration of cells by a purely optically induced process.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

COURVOISIER, Sébastien et al. Plasmonic Tipless Pyramid Arrays for Cell Poration. In: Nano letters, 2015, vol. 15, n° 7, p. 4461–4466. doi: 10.1021/acs.nanolett.5b01697

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1530-6984
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Technical informations

Creation

02/06/2016 11:25:00

First validation

02/06/2016 11:25:00

Update

15/03/2023 00:26:10

Status update

15/03/2023 00:26:10

Last indexation

31/10/2024 03:37:29
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