A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells

Saini, Camille; Petrenko, Volodymyr; Pulimeno, Pamela; Giovannoni, Laurianne; Berney, Thierry; Hebrok, M; Howald, Cédric; Dermitzakis, E T; Dibner, Charna

doi:10.1111/dom.12616

Scientific article

English

A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells

ContributorsSaini, Camille; Petrenko, Volodymyr; Pulimeno, Pamela; Giovannoni, Laurianne; Berney, Thierry; Hebrok, M; Howald, Cédric; Dermitzakis, E T; Dibner, Charna

Published inDiabetes, obesity & metabolism, vol. 18, no. 4, p. 355-365

Publication date2016

Abstract

To determine the impact of a functional human islet clock on insulin secretion and gene transcription.

Keywords

Circadian bioluminescence
Circadian clock
Human pancreatic islet
Insulin secretion
RNA sequencing

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research groups

Citation (ISO format)

SAINI, Camille et al. A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells. In: Diabetes, obesity & metabolism, 2016, vol. 18, n° 4, p. 355–365. doi: 10.1111/dom.12616

Article (Accepted version)

Identifiers

PID : unige:84220
DOI : 10.1111/dom.12616
PMID : 26662378

Journal ISSN1462-8902

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A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells

To determine the impact of a functional human islet clock on insulin secretion and gene transcription.

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