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The Confidence Information Ontology: a step towards a standard for asserting confidence in annotations

Bastian, Frederic B
Chibucos, Marcus C
Giglio, Michelle
Holliday, Gemma L
Huang, Hong
Lewis, Suzanna E
Niknejad, Anne
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Published in Database. 2015, vol. 2015, p. bav043
Abstract Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years. However, the reliability of these annotations varies; it has thus become necessary to be able to assess the confidence in annotations. Although several resources already provide confidence information about the annotations that they produce, a standard way of providing such information has yet to be defined. This lack of standardization undermines the propagation of knowledge across resources, as well as the credibility of results from high-throughput analyses. Seeded at a workshop during the Biocuration 2012 conference, a working group has been created to address this problem. We present here the elements that were identified as essential for assessing confidence in annotations, as well as a draft ontology--the Confidence Information Ontology--to illustrate how the problems identified could be addressed. We hope that this effort will provide a home for discussing this major issue among the biocuration community. Tracker URL: https://github.com/BgeeDB/confidence-information-ontology Ontology URL: https://raw.githubusercontent.com/BgeeDB/confidence-information-ontology/master/src/ontology/cio-simple.obo
Keywords Biological OntologiesCongresses as TopicData Curation/standards
PMID: 25957950
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Article (Published version) (673 Kb) - public document Free access
Research group Calipho (80)
Projects SERI
Swiss National Science Foundation (grant number 31003A_153341)
(ISO format)
BASTIAN, Frederic B et al. The Confidence Information Ontology: a step towards a standard for asserting confidence in annotations. In: Database, 2015, vol. 2015, p. bav043. https://archive-ouverte.unige.ch/unige:83908

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Deposited on : 2016-05-27

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