Sorne have asserted that altering the genetics of human germinal cells would be an assault to human dignity, others that it would lead down a slippery slope with dire consequences. What is your assessment of the eventual possibilities and dangers of human germline engineering, and what are your biggest fears about its implementation? Wou Id humanity be better off in a distant future where no direct modification of the genetics of human germline cells were allowed, or in one where significant modification were available?