UNIGE document Scientific Article
previous document  unige:83801  next document
add to browser collection
Title

Aryl Hydrocarbon Receptor Activation in Acne Vulgaris Skin: A Case Series from the Region of Naples, Italy

Authors
Fabbrocini, Gabriella
De Vita, Valerio
Published in Dermatology. 2015, vol. 231, no. 4, p. 334-8
Abstract Dioxins are persistent organic pollutants present in the environment. They exert their biological effects by binding to an intracellular receptor, the aryl hydrocarbon receptor (AhR). Activation of AhR leads to the induction of cytochrome p450 1A1 (CYP1A1). Expression of CYP1A1 in human skin is a key marker for AhR activation, and it may induce comedogenesis resulting in acne-like lesions known as chloracne/metabolising acquired dioxin-induced skin hamartomas (MADISH). The contribution of this pathway in patients seen in a busy acne clinic is unknown.
Keywords Aryl hydrocarbon receptorAcneDioxinSmokingCYP1A1ChloracneMetabolising acquired dioxin-induced skin hamartomas
Identifiers
PMID: 26440531
Full text
Article (Author postprint) (363 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Rôle du CD44 (809)
La recherche en biochimie dermatologique (652)
Citation
(ISO format)
FABBROCINI, Gabriella et al. Aryl Hydrocarbon Receptor Activation in Acne Vulgaris Skin: A Case Series from the Region of Naples, Italy. In: Dermatology, 2015, vol. 231, n° 4, p. 334-8. https://archive-ouverte.unige.ch/unige:83801

171 hits

2 downloads

Update

Deposited on : 2016-05-23

Export document
Format :
Citation style :