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Scientific article
Review
English

Two Ways to Get Mad at Kinetochores

ContributorsMeraldi, Patrickorcid
Published inDevelopmental cell, vol. 35, no. 5, p. 535-536
Publication date2015
Abstract

The spindle assembly checkpoint ensures that mitotic cells only segregate their sister chromatids once all chromosomes are attached via kinetochores by microtubules of the mitotic spindle. Reporting in Developmental Cell, Silió et al. (2015) show that in human cells the signaling cascade controlling the checkpoint operates through two separate branches.

Keywords
  • Cell Cycle Proteins/metabolism
  • Chromosomal Proteins, Non-Histone/metabolism
  • Humans
  • Kinetochores/metabolism
  • Microtubule-Associated Proteins/metabolism
Citation (ISO format)
MERALDI, Patrick. Two Ways to Get Mad at Kinetochores. In: Developmental cell, 2015, vol. 35, n° 5, p. 535–536. doi: 10.1016/j.devcel.2015.11.021
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ISSN of the journal1534-5807
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