UNIGE document Scientific Article
previous document  unige:82651  next document
add to browser collection
Title

Apoptosis: bombarding the mitochondria

Authors
Published in Essays in biochemistry. 2003, vol. 39, p. 41-51
Abstract Mitochondria play a central role in apoptosis triggered by many stimuli. They integrate death signals through Bcl-2 family members and co-ordinate caspase activation through the release of apoptogenic factors that are normally sequestered in the mitochondrial intermembrane space. The release of these proteins is the result of the outer mitochondrial membrane becoming permeable. In addition, mitochondria can initiate apoptosis through the production of reactive oxygen species.
Keywords AnimalsApoptosisCaenorhabditis elegans/metabolismGene Expression RegulationMitochondria/metabolism/physiologyModelsBiologicalOxygen/metabolismProto-Oncogene Proteins c-bcl-2/metabolism
Identifiers
PMID: 14585073
Full text
Article (Published version) (111 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
PARONE, Philippe et al. Apoptosis: bombarding the mitochondria. In: Essays in biochemistry, 2003, vol. 39, p. 41-51. https://archive-ouverte.unige.ch/unige:82651

94 hits

1 download

Update

Deposited on : 2016-04-12

Export document
Format :
Citation style :