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Synthesis and anti-HIV activity of 3′-deoxy-3′-(N-hydroxyamino) analogues of nucleosides

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Capek, Karel
Published in Bioorganic & Medicinal Chemistry Letters. 1992, vol. 2, no. 12, p. 1723-1728
Abstract 3′-Deoxy analogues of thymidine and uridine bearing a 3′-N-alkyl-(or N-aralkyl) -N-hydroxyamino group either on the α or the β face of the furanose ring have been prepared. One of these, exhibited a moderate anti-HIV activity.
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TRONCHET, Jean Marcel Julien et al. Synthesis and anti-HIV activity of 3′-deoxy-3′-(N-hydroxyamino) analogues of nucleosides. In: Bioorganic & Medicinal Chemistry Letters, 1992, vol. 2, n° 12, p. 1723-1728. https://archive-ouverte.unige.ch/unige:82362

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Deposited on : 2016-04-05

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