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Title

Towards the structure of the mammalian signal recognition particle

Authors
Wild, Klemens
Weichenrieder, Oliver
Sinning, Irmgard
Cusack, Stephen
Published in Current Opinion in Structural Biology. 2002, vol. 12, no. 1, p. 72-81
Abstract The signal recognition particle (SRP) is a ubiquitous ribonucleoprotein particle involved in the co-translational targeting of proteins to membranes. Crystal structures are now available for three protein–RNA subcomplexes from the SRP, which give insights into fundamental aspects of protein–RNA recognition, the assembly of stable ribonucleoprotein particles and the mechanism of action of the SRP.
Keywords Signal recognition particleRibonucleoproteinProtein-RNA interactionsX-ray crystallographyTetraloop7SL RNASRP9/14SRP54FfhAlu domainBiochemistryCell biologyStructural biology
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WILD, Klemens et al. Towards the structure of the mammalian signal recognition particle. In: Current Opinion in Structural Biology, 2002, vol. 12, n° 1, p. 72-81. https://archive-ouverte.unige.ch/unige:82361

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Deposited on : 2016-04-05

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