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Title

Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance

Authors
Tran Thang, Nhu Nam
Abdo, German
Seium-Neberay, Yodit
Verbist, Marie-Christine
Rufenacht, Daniel
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Published in Supportive Care in Cancer. 2008, vol. 16, no. 8, p. 891-6
Abstract GOALS OF WORK: Bone pain and functional impairment are major concerns for multiple myeloma (MM) patients. The goal of this study was to better define the role of percutaneous cementoplasty (PC) in improving their quality of life. MATERIALS AND METHODS: This retrospective analysis included 28 consecutive heavily pretreated MM patients managed at our institution between 1996 and 2002. They underwent a total of 34 PC procedures for the treatment of 117 vertebrae and 2 iliac sites and were evaluated at 1 month. MAIN RESULTS: Significant pain reduction of >50% was obtained after 83% of the procedures, with a mean visual analogous score decreasing from 7.48/10 to 2.1/10 (p < 0.001). It resulted in a complete interruption of opiate analgesic consumption after 59.3% of the procedures, with a mean decrease of 70.4% in the opiate dose. Functional impairment was evaluated with the Eastern Cooperative Oncology Group (ECOG) performance status scale, with mean scores improving from 1.9 to 0.86 after the procedures (p = 0.001). There was no major complication. CONCLUSION: PC is a safe, feasible, and efficient approach for the treatment of bone pain and disability in MM patients.
Keywords AdultAgedAged 80 and overFemaleFractures Bone/complications/etiology/prevention & control/surgeryHumansMaleMiddle AgedMultiple Myeloma/complications/pathologyPain/etiology/prevention & control/surgeryPain MeasurementPhlebographyRetrospective StudiesSpinal Fractures/complications/etiology/prevention & control/surgeryVertebroplasty/instrumentation/methodsYoung Adult
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PMID: 17960432
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Research group Immunothérapie des cancers (42)
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TRAN THANG, Nhu Nam et al. Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance. In: Supportive Care in Cancer, 2008, vol. 16, n° 8, p. 891-6. https://archive-ouverte.unige.ch/unige:823

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Deposited on : 2009-02-17

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