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Title

Practical, solvent-free, one-pot synthesis of C2-symmetrical secondary amines

Authors
Ditrich, Klaus
Published in Tetrahedron Letters. 2004, vol. 45, no. 7, p. 1449-1451
Abstract A novel one-pot reductive amination of ketones using the combination Ti(OiPr)4/H2/Pd–C is reported. This practical procedure does not require any solvent, and affords C2-symmetrical secondary amines in high yields and excellent diastereoselectivities. A novel one-pot reductive amination of ketones using the combination Ti(OiPr)4/H2/Pd–C is reported. This practical procedure does not require any solvent and affords C2-symmetrical secondary amines in high yields and excellent diastereoselectivities.
Keywords Reductive aminationC2-symmetryChiral aminesTitanium isopropoxide
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ALEXAKIS, Alexandre et al. Practical, solvent-free, one-pot synthesis of C2-symmetrical secondary amines. In: Tetrahedron Letters, 2004, vol. 45, n° 7, p. 1449-1451. https://archive-ouverte.unige.ch/unige:8212

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Deposited on : 2010-06-21

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