Organocopper conjugate addition reaction in the presence of trimethylchlorosilane

Alexakis, Alexandre; Berlan, J.; Besace, Y.

doi:10.1016/S0040-4039(86)80044-2

Scientific article

Letter

English

Organocopper conjugate addition reaction in the presence of trimethylchlorosilane

ContributorsAlexakis, Alexandre; Berlan, J.; Besace, Y.

Published inTetrahedron letters, vol. 27, no. 9, p. 1047-1050

Publication date1986

Abstract

In the presence of TMSCl, the conjugate addition of organocuprates to various a, ß-unsaturated esters, amides, ketones and nitriles is greatly improved. The reaction is faster, the yields are very high and the reaction is very clean.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

ALEXAKIS, Alexandre, BERLAN, J., BESACE, Y. Organocopper conjugate addition reaction in the presence of trimethylchlorosilane. In: Tetrahedron letters, 1986, vol. 27, n° 9, p. 1047–1050. doi: 10.1016/S0040-4039(86)80044-2

Article (Published version)

Identifiers

PID : unige:8209
DOI : 10.1016/S0040-4039(86)80044-2

Journal ISSN0040-4039

596views

1downloads

Creation21/06/2010 14:44:38

First validation21/06/2010 14:44:38

Update time14/03/2023 15:48:34

Status update14/03/2023 15:48:34

Last indexation29/10/2024 15:35:12

Archive ouverte UNIGE

Organocopper conjugate addition reaction in the presence of trimethylchlorosilane

In the presence of TMSCl, the conjugate addition of organocuprates to various a, ß-unsaturated esters, amides, ketones and nitriles is greatly improved. The reaction is faster, the yields are very high and the reaction is very clean.

Technical informations