Vinyl-copper derivatives 151. An efficient synthesis of polysubstituted conjugated dienes

Jabri, N.; Alexakis, Alexandre; Normant, Jean F.

doi:10.1016/S0040-4039(00)87166-X

Scientific article

Letter

English

Vinyl-copper derivatives 151. An efficient synthesis of polysubstituted conjugated dienes

ContributorsJabri, N.; Alexakis, Alexandre; Normant, Jean F.

Published inTetrahedron letters, vol. 23, no. 15, p. 1589-1592

Publication date1982

Abstract

Magnesium vinyl-copper derivatives, obtained by carbocupration of terminal alkynes, couple with 1-halo-1-alkenes, in the presence of Pd(PPh3)4 catalyst, to afford polysubstituted conjugated dienes in high yield and excellent stereoisomeric purity.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

JABRI, N., ALEXAKIS, Alexandre, NORMANT, Jean F. Vinyl-copper derivatives 151. An efficient synthesis of polysubstituted conjugated dienes. In: Tetrahedron letters, 1982, vol. 23, n° 15, p. 1589–1592. doi: 10.1016/S0040-4039(00)87166-X

Article (Published version)

Identifiers

PID : unige:8199
DOI : 10.1016/S0040-4039(00)87166-X

Journal ISSN0040-4039

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Vinyl-copper derivatives 151. An efficient synthesis of polysubstituted conjugated dienes

Magnesium vinyl-copper derivatives, obtained by carbocupration of terminal alkynes, couple with 1-halo-1-alkenes, in the presence of Pd(PPh3)4 catalyst, to afford polysubstituted conjugated dienes in high yield and excellent stereoisomeric purity.

Technical informations