Satellite derived solar radiation is nowadays a good alternative to ground measurements for renewable energy applications. It has the advantage to provide data with a good accuracy, the best time and space granularity, in term of real time series and average year such as TMY. This report presents results of a long term validation in the European and Mediteranean regions of the irradiance evaluated by the HelioClim-3 scheme in hourly, daily and monthly values, and seven average products on an annual basis. The performance is also put forward with the natural interannual variability. The main results are: - the accuracy of the derived hourly global irradiance reaches 20% (standard deviation) with no bias, and 46% for the beam component with a 6% to 9% mean bias, - the main improvement from version 4 to version 5 comes from the use of a new clear syk model with sub-daily aerosol data as input, - some systematic patterns are pointed out, depending on the sky type, the site latitude, the aerosol optical depth and the ground snow cover, - the overall annual uncertainty of the HelioClim-3 scheme is situated within one interannual variability standard deviation for the global component, and within two standard deviations for the beam irradiation, - the overall performance for the beam component is slightly worse for version 5, but the frequency distributions are improved, particularly for high irradiance values.