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Scientific article
English

Chiral aminal templates 5. Preparation of chiral 3-carboxaldehydes-1,4-dihydropyridines

Published inSynlett, no. 2, p. 111-113
Publication date1991
Abstract

Organocopper reagents react with 1-acylpyridinium salts, bearing in the 3 position a chiral aminal [1-acyl-3-(trans-1,3-dimethyl-4, 5-diphenylimidazolidin-2-yl)pyridinium salts], to give after acidic hydrolysis chiral 4-substituted 1-acyl-1, 4-dihydropyridine-3-carboxaldehydes in high optical purity and in good chemical yield.

Affiliation Not a UNIGE publication
Citation (ISO format)
GOSMINI, Romain et al. Chiral aminal templates 5. Preparation of chiral 3-carboxaldehydes-1,4-dihydropyridines. In: Synlett, 1991, n° 2, p. 111–113. doi: 10.1055/s-1991-20646
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ISSN of the journal0936-5214
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