Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway
Published inProceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 8, p. 2503-2508
Publication date2015
Abstract
Keywords
- Animals
- Antibodies, Monoclonal/pharmacology/therapeutic use
- Blood Glucose/metabolism
- Diabetes Mellitus, Experimental/blood/drug therapy/pathology
- Diabetes Mellitus, Type 1/blood/drug therapy/pathology
- Female
- Glucagon/secretion
- Humans
- Insulin/therapeutic use
- Mice
- Mice, Inbred NOD
- Paracrine Communication/drug effects
- Rats
- Rats, Zucker
- Receptors, Glucagon/immunology
Affiliation
Research group
Citation (ISO format)
WANG, May-Yun et al. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. In: Proceedings of the National Academy of Sciences of the United States of America, 2015, vol. 112, n° 8, p. 2503–2508. doi: 10.1073/pnas.1424934112
Main files (1)
Article (Published version)
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Identifiers
- PID : unige:81175
- DOI : 10.1073/pnas.1424934112
- PMID : 25675519
ISSN of the journal0027-8424