en
Scientific article
Letter
English

Conceptually new chiral tertiary C2 symmetric diamines in asymmetric synthesis

Published inTetrahedron letters, vol. 44, no. 49, p. 8893-8895
Publication date2003
Abstract

New chiral diamines were prepared, based on the cyclohexane diamine core. The two different substituents on each nitrogen allow this heteroatom to become a stereogenic center upon chelation with a metal, such as lithium. The enantioselective addition of MeLi to imines, with ee's up to 68%, illustrates the validity of this concept.

Keywords
  • Asymmetric synthesis
  • Diamines
  • Organolithiums
  • Imines
  • C2 symmetry
Citation (ISO format)
KIZIRIAN, Jean-Claude, CAILLE, Jean-Claude, ALEXAKIS, Alexandre. Conceptually new chiral tertiary C2 symmetric diamines in asymmetric synthesis. In: Tetrahedron letters, 2003, vol. 44, n° 49, p. 8893–8895. doi: 10.1016/j.tetlet.2003.09.171
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0040-4039
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