Regio and enantioselective synthesis of 4-carbomethoxymethy-1,4-dihydropyridines

Raussou, Sabine; Gosmini, Romain; Mangeney, Pierre; Alexakis, Alexandre; Commerçon, Monique

doi:10.1016/S0040-4039(00)73518-0

Scientific article

Letter

English

Regio and enantioselective synthesis of 4-carbomethoxymethy-1,4-dihydropyridines

ContributorsRaussou, Sabine; Gosmini, Romain; Mangeney, Pierre; Alexakis, Alexandre; Commerçon, Monique

Published inTetrahedron letters, vol. 35, no. 30, p. 5433-5436

Publication date1994

Abstract

Regio and enantioselective 1,4 addition of ethoxyvinyl copper reagent on a pyridine bearing in position 3 a chiral aminal is described. This reaction allows the synthesis of various chiral N-acyl-4-methoxymethyl-1,4-dihydropyridines.

Affiliation Not a UNIGE publication

Citation (ISO format)

RAUSSOU, Sabine et al. Regio and enantioselective synthesis of 4-carbomethoxymethy-1,4-dihydropyridines. In: Tetrahedron letters, 1994, vol. 35, n° 30, p. 5433–5436. doi: 10.1016/S0040-4039(00)73518-0

Article (Published version)

Identifiers

PID : unige:8086
DOI : 10.1016/S0040-4039(00)73518-0

ISSN of the journal0040-4039

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Regio and enantioselective synthesis of 4-carbomethoxymethy-1,4-dihydropyridines

Regio and enantioselective 1,4 addition of ethoxyvinyl copper reagent on a pyridine bearing in position 3 a chiral aminal is described. This reaction allows the synthesis of various chiral N-acyl-4-methoxymethyl-1,4-dihydropyridines.

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