Preventive administration of UDCA after liver transplantation for primary biliary cirrhosis is associated with a lower risk of disease recurrence

Bosch, Alexie; Dumortier, Jérôme; Maucort-Boulch, Delphine; Scoazec, Jean-Yves; Wendum, Dominique; Conti, Filomena; Morard, Isabelle; Rubbia-Brandt, Laura; Terris, Benoit; Radenne, Sylvie; Abenavoli, Ludovico; Poupon, Raoul; Chazouillères, Olivier; Calmus, Yvon; Boillot, Olivier; Giostra, Emiliano; Corpechot, Christophe

doi:10.1016/j.jhep.2015.07.038

Scientific article

English

Preventive administration of UDCA after liver transplantation for primary biliary cirrhosis is associated with a lower risk of disease recurrence

ContributorsBosch, Alexie; Dumortier, Jérôme; Maucort-Boulch, Delphine; Scoazec, Jean-Yves; Wendum, Dominique; Conti, Filomena; Morard, Isabelle; Rubbia-Brandt, Laura; Terris, Benoit; Radenne, Sylvie; Abenavoli, Ludovico; Poupon, Raoul; Chazouillères, Olivier; Calmus, Yvon; Boillot, Olivier; Giostra, Emiliano; Corpechot, Christophe

Published inJournal of hepatology, vol. 63, no. 6, p. 1449-1458

Publication date2015

Abstract

Recurrence of primary biliary cirrhosis (PBC) after liver transplantation (LT) is not rare and can occasionally lead to severe graft dysfunction and retransplantation. Ursodeoxycholic acid (UDCA) is a safe and effective treatment for PBC. However, whether preventive administration of UDCA after LT could lower the incidence of PBC recurrence is unknown.

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Citation (ISO format)

BOSCH, Alexie et al. Preventive administration of UDCA after liver transplantation for primary biliary cirrhosis is associated with a lower risk of disease recurrence. In: Journal of hepatology, 2015, vol. 63, n° 6, p. 1449–1458. doi: 10.1016/j.jhep.2015.07.038

Article (Accepted version)

Identifiers

PID : unige:80788
DOI : 10.1016/j.jhep.2015.07.038
PMID : 26282232

Journal ISSN0168-8278

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Preventive administration of UDCA after liver transplantation for primary biliary cirrhosis is associated with a lower risk of disease recurrence

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