Stereochemical effects of trimethylsilyl chloride (TMSCl) on the conjugate addition of organocopper reagents

Alexakis, Alexandre; Sedrani, R.; Mangeney, Pierre

doi:10.1016/S0040-4039(00)94551-9

Scientific article

Letter

English

Stereochemical effects of trimethylsilyl chloride (TMSCl) on the conjugate addition of organocopper reagents

ContributorsAlexakis, Alexandre; Sedrani, R.; Mangeney, Pierre

Published inTetrahedron letters, vol. 31, no. 3, p. 345-348

Publication date1990

Abstract

The stereochemical course of the conjugate addition of organocopper reagents, in the presence of TMSCl, is not affected by remote chelation effects, whereas in its absence, the latter may predominate. By this way, it is possible to distinguish, the relative effects of the chelation and of the steric hindrance.

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Citation (ISO format)

ALEXAKIS, Alexandre, SEDRANI, R., MANGENEY, Pierre. Stereochemical effects of trimethylsilyl chloride (TMSCl) on the conjugate addition of organocopper reagents. In: Tetrahedron letters, 1990, vol. 31, n° 3, p. 345–348. doi: 10.1016/S0040-4039(00)94551-9

Article (Published version)

Identifiers

PID : unige:8078
DOI : 10.1016/S0040-4039(00)94551-9

Journal ISSN0040-4039

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Stereochemical effects of trimethylsilyl chloride (TMSCl) on the conjugate addition of organocopper reagents

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