Mild protection and deprotection of alcohols as ter-butyl ethers in the field of pheromone synthesis

Alexakis, Alexandre; Gardette, M.; Colin, S.

doi:10.1016/0040-4039(88)85055-X

Scientific article

Letter

English

Mild protection and deprotection of alcohols as ter-butyl ethers in the field of pheromone synthesis

ContributorsAlexakis, Alexandre; Gardette, M.; Colin, S.

Published inTetrahedron letters, vol. 29, no. 24, p. 2951-2954

Publication date1988

Abstract

α,ω-Halohydrins and Ω-acetylenic alcohols are protected as t-butyl ethers by reaction with isobutene and an acid catalyst : Amberlyst H-15. t-Butyl ethers are, in turn, cleaved to acetates by Ac2O and 10% FeCl3 in Et2O solvent. Under these mild conditions conjugated dienic systems are neither destroyed nor isomerized.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

ALEXAKIS, Alexandre, GARDETTE, M., COLIN, S. Mild protection and deprotection of alcohols as ter-butyl ethers in the field of pheromone synthesis. In: Tetrahedron letters, 1988, vol. 29, n° 24, p. 2951–2954. doi: 10.1016/0040-4039(88)85055-X

Article (Published version)

Identifiers

PID : unige:8072
DOI : 10.1016/0040-4039(88)85055-X

Journal ISSN0040-4039

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Mild protection and deprotection of alcohols as ter-butyl ethers in the field of pheromone synthesis

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