Resolution and determination of enantiomeric excesses of chiral aldehydes via chiral imidazolidines

Mangeney, Pierre; Alexakis, Alexandre; Normant, Jean F.

doi:10.1016/0040-4039(88)85258-4

Scientific article

Letter

English

Resolution and determination of enantiomeric excesses of chiral aldehydes via chiral imidazolidines

ContributorsMangeney, Pierre; Alexakis, Alexandre; Normant, Jean F.

Published inTetrahedron letters, vol. 29, no. 22, p. 2677-2680

Publication date1988

Abstract

Enantiomeric purity of chiral aldehydes was determined by NMR analysis of derived imidazolidines. The diastereomeric imidazolidines were easily separted by silica gel column and converted into enantiomerically pure aldehyde by acid hydrolysis.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

MANGENEY, Pierre, ALEXAKIS, Alexandre, NORMANT, Jean F. Resolution and determination of enantiomeric excesses of chiral aldehydes via chiral imidazolidines. In: Tetrahedron letters, 1988, vol. 29, n° 22, p. 2677–2680. doi: 10.1016/0040-4039(88)85258-4

Article (Published version)

Identifiers

PID : unige:8071
DOI : 10.1016/0040-4039(88)85258-4

Journal ISSN0040-4039

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Resolution and determination of enantiomeric excesses of chiral aldehydes via chiral imidazolidines

Enantiomeric purity of chiral aldehydes was determined by NMR analysis of derived imidazolidines. The diastereomeric imidazolidines were easily separted by silica gel column and converted into enantiomerically pure aldehyde by acid hydrolysis.

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