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Enantioselective addition of organolithium reagents on isoquinoline

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Published in Tetrahedron: Asymmetry. 2002, vol. 13, no. 19, p. 2117-2122
Abstract 1-Methyl-1,2-dihydroisoquinoline and 1-butyl-1,2-dihydroisoquinoline were obtained by enantioselective addition of organolithium reagents on the isoquinoline. (-)-Sparteine was used as an external catalytic chiral ligand and an enantiomeric excess of 57% could be obtained.
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ALEXAKIS, Alexandre, AMIOT, Franck. Enantioselective addition of organolithium reagents on isoquinoline. In: Tetrahedron: Asymmetry, 2002, vol. 13, n° 19, p. 2117-2122. https://archive-ouverte.unige.ch/unige:8053

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Deposited on : 2010-06-21

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