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Radical cyclizations of 1,4-dihydropyridines. Synthesis of chiral fused nitrogen heterocycles. Synthesis of Lupinine and Epilupinine

Authors
Mangeney, Pierre
Hamon, Louis
Raussou, Sabine
Urbain, Nicolas
Published in Tetrahedron. 1998, vol. 54, no. 35, p. 10349-10362
Abstract Radical cyclizations of 1-(4-iodoalkanoyl)-3-formyl-4-methyl-1,4-dihydropyridines are described and discussed. A regio and diasteroselective reaction is obtained under ultrasonic conditions. An application to the synthesis of lupinine and epilupinine is shown.
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MANGENEY, Pierre et al. Radical cyclizations of 1,4-dihydropyridines. Synthesis of chiral fused nitrogen heterocycles. Synthesis of Lupinine and Epilupinine. In: Tetrahedron, 1998, vol. 54, n° 35, p. 10349-10362. https://archive-ouverte.unige.ch/unige:8046

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Deposited on : 2010-06-21

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