Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

Polet, Damien; Alexakis, Alexandre

doi:10.1021/ol050350w

Scientific article

Letter

English

Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

ContributorsPolet, Damien; Alexakis, Alexandre

Published inOrganic letters, vol. 7, no. 8, p. 1621-1624

Publication date2005

Abstract

A comparative kinetic study of seven ligands is presented which clearly shows that a slight difference in the substitution pattern of the aryl group on the amine moiety of the ligand dramatically alters the activity of the resulting iridium catalyst. Ligand L6 shows the most impressive kinetics as well as the highest enantioselectivities.

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

POLET, Damien, ALEXAKIS, Alexandre. Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution. In: Organic letters, 2005, vol. 7, n° 8, p. 1621–1624. doi: 10.1021/ol050350w

Article (Published version)

Identifiers

PID : unige:8043
DOI : 10.1021/ol050350w
PMID : 15816767

ISSN of the journal1523-7052

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Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

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