Organolithium chiral Lewis base BF3 : versatile combination for the enantioselective desymmetrisation of meso-epoxides

Browse by...

Deposit

Highlights

More informations

Title		Organolithium chiral Lewis base BF3 : versatile combination for the enantioselective desymmetrisation of meso-epoxides
Authors		Vrancken, Emmanuel Alexakis, Alexandre Mangeney, Pierre
Published in		European Journal of Organic Chemistry. 2005, vol. 2005, no. 7, p. 1354-1366
Abstract		BF3 can be used in combination with organolithium/strong Lewis base complexes for the enantioselective nucleophilic ring-opening or the carbenoidic rearrangement of various meso-oxiranes with excellent yields and ee values of up to 87 %. Mechanistic aspects of these reactions are considered.
Keywords		Boranes — Carbenoids — Lithium — Lewis bases — Synthetic methods
Identifiers		DOI: 10.1002/ejoc.200400745
Full text		Article (Published version) - Limited access to UNIGE
Structures		Faculté des sciences / Section de chimie et biochimie / Département de chimie organique
Citation (ISO format)		VRANCKEN, Emmanuel, ALEXAKIS, Alexandre, MANGENEY, Pierre. Organolithium chiral Lewis base BF3 : versatile combination for the enantioselective desymmetrisation of meso-epoxides. In: European Journal of Organic Chemistry, 2005, vol. 2005, n° 7, p. 1354-1366. https://archive-ouverte.unige.ch/unige:8034