Copper-catalyzed kinetic resolution of 1,3-cyclohexadiene monoepoxide with Grignard reagents

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Title		Copper-catalyzed kinetic resolution of 1,3-cyclohexadiene monoepoxide with Grignard reagents
Authors		Millet, Renaud Alexakis, Alexandre
Published in		Synlett. 2007, no. 3, p. 435-438
Abstract		Chiral ferrocenyl-based diphosphines lead to kinetic resolution of 1,3-cyclohexadiene monoepoxide with moderate to good enantioselectivity (up to 90% ee) and good regioselectivity with various Grignard reagents through an anti-SN2¢ pathway.
Keywords		Epoxides — Asymmetric synthesis — Grignard reagents — Catalysis — Copper
Identifiers		DOI: 10.1055/s-2007-967945
Full text		Article (Published version) - Limited access to UNIGE
Structures		Faculté des sciences / Section de chimie et biochimie / Département de chimie organique
Citation (ISO format)		MILLET, Renaud, ALEXAKIS, Alexandre. Copper-catalyzed kinetic resolution of 1,3-cyclohexadiene monoepoxide with Grignard reagents. In: Synlett, 2007, n° 3, p. 435-438. https://archive-ouverte.unige.ch/unige:8027