Scientific article
English

On the use of phosphramidite ligands in copper-catalyzed asymmetric transformations with trialkylaluminium reagents

Published in

Organic letters, vol. 8, no. 16, p. 3581-3584

Publication date

2006

Abstract

Phosphoramidites based on BINOL readily react with trimethylaluminum in "noncoordinating" solvents, leading to the corresponding aminophosphine which is the real ligand in copper-catalyzed asymmetric transformations. This artifact explains the experimental differences in the asymmetric ring opening of meso bicyclic hydrazines using dialkylzinc or trialkylaluminum reagents as nucleophiles.

Citation (ISO format)

BOURNAUD, Chloee Julie et al. On the use of phosphramidite ligands in copper-catalyzed asymmetric transformations with trialkylaluminium reagents. In: Organic letters, 2006, vol. 8, n° 16, p. 3581–3584. doi: 10.1021/ol061471e

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Article (Published version)

Identifiers

Journal ISSN

1523-7052
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Technical informations

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21/06/2010 14:15:41

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21/06/2010 14:15:41

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14/03/2023 15:47:45

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