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Title

Effect of hydrosoluble vitamin E on erythrocyte membrane lipid composition in patients with advanced cirrhosis: An open-label pilot trial
Authors
Restellini, Sophie
Alaei, Mahnaz
Matthes, Thomas
Kherad, Omar
Moschetta, Antonio
Spahr, Laurent François Joséph
Published in Hepatology research. 2015, vol. 45, no. 8, p. 890-897
Abstract Deficiency in vitamin E, a natural antioxidant, participates in abnormal erythrocyte membrane lipids, structural alterations and hemolysis in advanced cirrhosis. Poor absorption of fat-soluble vitamins limits full correction of deficiency with standard formulations in cirrhosis with cholestasis. The aim of the present study was to examine safety and effects of tocofersolan, a water-soluble derivative of vitamin E, on erythrocyte membrane lipids and anemia in patients with biopsy-proven advanced cirrhosis, vitamin E deficiency and hemolysis.
Identifiers
PMID: 25286983
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Article (Published version) (602 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Research group Analyses cellulaires et moléculaires des hémopathies malignes (929)
Citation
(ISO format) 		RESTELLINI, Sophie et al. Effect of hydrosoluble vitamin E on erythrocyte membrane lipid composition in patients with advanced cirrhosis: An open-label pilot trial. In: Hepatology research, 2015, vol. 45, n° 8, p. 890-897. doi: 10.1111/hepr.12430 https://archive-ouverte.unige.ch/unige:79942

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Deposited on : 2016-01-22

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