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Effect of hydrosoluble vitamin E on erythrocyte membrane lipid composition in patients with advanced cirrhosis: An open-label pilot trial |
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Published in | Hepatology research. 2015, vol. 45, no. 8, p. 890-897 | |
Abstract | Deficiency in vitamin E, a natural antioxidant, participates in abnormal erythrocyte membrane lipids, structural alterations and hemolysis in advanced cirrhosis. Poor absorption of fat-soluble vitamins limits full correction of deficiency with standard formulations in cirrhosis with cholestasis. The aim of the present study was to examine safety and effects of tocofersolan, a water-soluble derivative of vitamin E, on erythrocyte membrane lipids and anemia in patients with biopsy-proven advanced cirrhosis, vitamin E deficiency and hemolysis. | |
Identifiers | DOI: 10.1111/hepr.12430 PMID: 25286983 | |
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Research group | Analyses cellulaires et moléculaires des hémopathies malignes (929) | |
Citation (ISO format) | RESTELLINI, Sophie et al. Effect of hydrosoluble vitamin E on erythrocyte membrane lipid composition in patients with advanced cirrhosis: An open-label pilot trial. In: Hepatology research, 2015, vol. 45, n° 8, p. 890-897. doi: 10.1111/hepr.12430 https://archive-ouverte.unige.ch/unige:79942 |