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Title

The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis

Authors
Vermeij, Eline A
Koenders, Marije I
Bennink, Miranda B
Maurizi, Lionel
Hofmann, Heinrich
van den Berg, Wim B
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Published in PLOS ONE. 2015, vol. 10, no. 5, p. e0126687
Abstract Superparamagnetic Iron Oxide Nanoparticles (SPION) are used in diagnostic imaging of a variety of different diseases. For such in-vivo application, an additional coating with a polymer, for example polyvinyl alcohol (PVA), is needed to stabilize the SPION and prevent aggregation. As the particles are foreign to the body, reaction against the SPION could occur. In this study we investigated the effects that SPION may have on experimental arthritis after intra-articular (i.a.) or intravenous (i.v.) injection.
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PMID: 25955417
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Research group Imagerie cardiaque fonctionnelle (541)
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VERMEIJ, Eline A et al. The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis. In: PLOS ONE, 2015, vol. 10, n° 5, p. e0126687. https://archive-ouverte.unige.ch/unige:79641

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Deposited on : 2016-01-20

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